Neomercazole

Neomercazole

Carbimazole Tablets

Availability: In stock

$0.09

Neo-Mercazole tablets 5mg are used to treat hyperthyroidism or over-active thyroid, which causes thyrotoxicosis due to over production of thyroid hormone. The most common form of hyperthyroidism is Grave’s Disease or goitre, which is thought to be an autoimmune disease where autoantibodies called thyroid stimulating immunoglobulins bind to the receptor for Thyroid Stimulating Hormone (TSH) and cause loss of regulation of thyroid hormone production. Hyperthyroidism can also be caused by inflammation, a tumour or a virus infection. Symptoms of hyperthyroidism are due to increased production of thyroid hormone, which causes increased rate of metabolism. They include nervousness, restlessness, irritability difficulty concentrating, tiredness, rapid heartbeat, heat intolerance, increased perspiration, difficulty sleeping, hand tremors, weight loss, increased appetite, frequent bowel movements, and muscular weakness. Neo-Mercazole tablets 5mg are used to help induce permanent remission from thyrotoxicosis; also to restore normal thyroid function before thyroid surgery to remove whole or part of the thyroid gland; also before and after treatment with radioactive iodine for overactive thyroid.

Quantity Strength Unit Price Price Cart
100 Tablets Neomercazole 10mg $0.09 $9.00
200 Tablets Neomercazole 10mg $0.09 $18.00
400 Tablets Neomercazole 10mg $0.09 $35.00
100 Tablets Neomercazole 20mg $0.12 $12.00
200 Tablets Neomercazole 20mg $0.12 $24.00
400 Tablets Neomercazole 20mg $0.11 $45.00

Details

Mechanism of action:

Neo-Mercazole tablets 5mg contain carbimazole, which is a pro-drug and is rapidly metabolised after absorption into its active form methimazole. This metabolite inhibits the action of thyroid peroxidase, an enzyme that is involved in the coupling and iodination of thyroglobulin, which is important for the synthesis of thyroid hormone. Hyperthyroidism is due to an overactive thyroid gland and overproduction of thyroid hormone, which exists in two forms, thyroxine or levothyroxine, also known as T4 and liothyronine or L-triiodothyronine also known as T3. The production of thyroid hormone is normally regulated by thyroid stimulating hormone (TSH), a hormone produced by the pituitary gland in the hypothalamus, at the base of the brain, and it is this regulation that is deficient in Grave’s disease. Carbimazole in Neo-Mercazole tablets 5mg blocks the synthesis of thyroid hormone and thereby helps restore normal levels.

Dosage and how to use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It can be taken with or without food, but it is better to take Neo-Mercazole 10mg Tablet at a fixed time.

Contraindication:

NeoMercazole is contraindicated in patients with:

• Hypersensitivity to carbimazole or to any of the excipients listed in section 6.1

• Serious pre-existing haematological conditions

• Severe hepatic insufficiency

Sideeffects:

Skin rash, Headache, Skin pigmentation, Pain, Joint stiffness, Nausea, Paresthesia (tingling or pricking sensation), Hair loss.

Missed dose:

If you miss a dose of Neo-Mercazole tablets 5mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

Overdose:

Overdose produces untoward side effects on one or various organs in the body. A drug is excreted in the kidney or metabolized in the liver most of the times. This process goes without any hurdles when taken in normal dose, but when taken in an overdose, the body is not able to metabolize it or send it out properly which causes the effects of anoverdose

Safety measures:

. AdiabeticorHypertensivepatientneedtobewarnedaboutfewdruginteractions.Aknownhypersensitivitypatientneedstobecarefulaboutthereactionsoranaphylacticshock.Apregnantwomanorabreastfeedingwomanshouldbewarnedofcertaindrugs.AHepatitis[liverdisease]patientoracardiacpatientshouldavoidfewdrugs.

Storage:

You should store your Neo-Mercazole below 25°C in a cool dry place.